The Importance of Alpha-fetoprotein (AFP) in Screening for Liver Cancer

Liver cancer is a serious health condition that can go undetected for years, making it difficult to treat. Fortunately, there is a test that can help detect liver cancer in its early stages. This test is called the alpha-fetoprotein (AFP) screening test.

What is AFP?

Alpha-fetoprotein (AFP) is a protein produced by the liver and the developing fetus. High levels of AFP in the bloodstream can be an indicator of liver cancer, as well as other conditions such as cirrhosis or hepatitis. Although not always the case, high levels of AFP are present in about 70% of patients with liver cancer.

AFP Screening for Liver Cancer

AFP screening is a blood test that can detect the presence of AFP in the bloodstream. If liver cancer is suspected, this test will be one of the first diagnostic tools used to confirm the diagnosis. It is important to note that the AFP test alone cannot diagnose liver cancer; other tests, such as imaging and biopsies, may also be necessary.

How is the AFP Screening Test Performed?

The AFP test is a simple blood test that can be performed in a clinic, hospital or at a laboratory. It involves drawing a small amount of blood from the patient's arm using a needle. The blood is then sent to a laboratory for analysis. Results are usually available within a few days.

Who Should Get an AFP Screening Test?

AFP screening is recommended for patients who are at high risk of developing liver cancer. Those at risk include patients with liver cirrhosis, chronic hepatitis B or C infection, or a family history of liver cancer. In addition, regular AFP testing is recommended for patients who have already been diagnosed with liver cancer to monitor the effectiveness of treatment and to detect any recurrence of the disease.


Early detection is essential for the successful treatment of liver cancer. AFP screening is an important diagnostic tool that can detect the presence of liver cancer in its early stages. Patients at high risk of developing liver cancer, as well as those who have already been diagnosed, should undergo regular AFP testing to monitor their condition. If you are at risk for liver cancer, talk to your doctor about the AFP screening test and other screening options. By taking a proactive approach to your health, you can increase your chances of successful treatment and recovery.